Now, I really hate to sound like a travel snob -- you know, the guy that goes someplace and then spends all his time telling you how it's not worth seeing -- but the Cistine Chapel just isn't worth seeing. I mean, everyone's seen that little section where God and Adam are touching fingers, and I don't dispute it's a nice picture. However, it's set in the middle of about ten thousand other pictures, all of which have mostly-naked people hanging out on clouds and doing strange things. Overall, the entire thing just looks silly. He should have quit while he was ahead. It's like some flesh-tone addict went on a graffiti binge in his bedroom. Granted, they're detailed and nice pictures. But, as the immortal Bob Ross once said, the key is choosing when to stop. Just say no.
Incidentally, photos are absolutely forbidden in the chapel, so rather than being disturbed by the insidiosuly noisy cameras, you are lulled into a sense of grandeur by the security guard loudly threatening and removing photographers every five seconds or so. Big improvement.